CSNK1A1 抗体
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Quick Overview for CSNK1A1 抗体 (ABIN498265)
抗原
See all CSNK1A1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of Casein Kinase I α protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
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纯度
- > 95 % (by SDS-PAGE)
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anti-Casein Kinase 1, alpha 1 (CSNK1A1) (Internal Region) antibody
CSNK1A1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyKD Validated CSNK1A1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB125 unconjugated Recombinant Antibody
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 100-200) antibodyCSNK1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 309-337), (C-Term) antibodyCSNK1A1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00886 unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 30-68), (N-Term) antibodyCSNK1A1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (pTyr294) antibodyCSNK1A1 适用: 人, 大鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 2-337), (Isoform alpha) antibodyCSNK1A1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyCSNK1A1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyCSNK1A1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 3C10F7 unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyCSNK1A1 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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别名
- Casein Kinase I alpha
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背景
- Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes examined to date. Casein kinase I family members, which include casein kinase Iα, Iγ, Iδ and Iε, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an α2β2 or an αα'β2 structure. The a catalytic subunit is stimulated by the β regulatory subunit, which undergoes autophosphorylation. Casein kinase II activity is high in the cytosol and nucleus of proliferating and differentiating cells. Casein kinase II is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.Synonyms: CK1, CKI-alpha, CSNK1A1
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分子量
- approx. 35 kDa
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基因ID
- 1452
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NCBI登录号
- NP_001883
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UniProt
- P48729
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途径
- WNT signaling, Hedgehog Signaling
抗原
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