CSNK1A1 抗体 (pTyr294)
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北京 101111
Quick Overview for CSNK1A1 抗体 (pTyr294) (ABIN6256701)
抗原
See all CSNK1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr294
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特异性
- Phospho-CK-1 alpha (Tyr294) Antibody detects endogenous levels of CK-1 alpha only when phosphorylated at PhoTyr294
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human Phospho-CK-1 alpha (Tyr294)
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亚型
- IgG
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应用备注
- WB 1:1000-3000 IHC 1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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别名
- CK-1 alpha
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背景
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Description: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis (PubMed:11955436, PubMed:1409656, PubMed:18305108). May play a role in keratin cytoskeleton disassembly and thereby, it may regulate epithelial cell migration (PubMed:23902688).
Gene: CSNK1A1
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分子量
- 38 kDa
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基因ID
- 1452
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UniProt
- P48729, Q8N752
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途径
- WNT signaling, Hedgehog Signaling
抗原
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