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Integrin beta 4 抗体

ITGB4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498235
发货至: 中国
  • 抗原 See all Integrin beta 4 (ITGB4) 抗体
    Integrin beta 4 (ITGB4)
    适用
    • 78
    • 26
    • 25
    • 3
    • 3
    人, 小鼠, 大鼠
    宿主
    • 56
    • 33
    • 7
    • 2
    克隆类型
    • 50
    • 48
    多克隆
    标记
    • 50
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    • 1
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    • 1
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    • 1
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    This Integrin beta 4 antibody is un-conjugated
    应用范围
    • 49
    • 40
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    • 28
    • 18
    • 13
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    • 9
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    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Integrin β4 protein.
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product ITGB4 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Integrin beta 4 (ITGB4)
    别名
    CD104 / Integrin beta-4 (ITGB4 产品)
    别名
    AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
    背景
    Integrins are heterodimers composed of noncovalently associated transmembrane α and β subunits. The 16 α and 8 β subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.Synonyms: GP150, ITGB4
    分子量
    approx. 202 kDa
    基因ID
    3691
    NCBI登录号
    NP_000204
    UniProt
    P16144
    途径
    Integrin Complex
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