TP53BP1 抗体
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北京 101111
Quick Overview for TP53BP1 抗体 (ABIN498186)
抗原
See all TP53BP1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of 53BP1 protein.
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity Chromatography using epitope-specific immunogen.
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anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 574-773) antibody
TP53BP1 适用: 人 IHC, WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6B3E10 unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) antibodyKD Validated TP53BP1 适用: 人 WB, FACS, IF (p) 宿主: 小鼠 Monoclonal 24GB13320 unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 350-400) antibodyTP53BP1 适用: 人, 小鼠 IHC, WB, FACS, IP 宿主: 兔 Monoclonal BL-250-1H11 unconjugated Recombinant Antibody
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1239-1972) antibodyTP53BP1 适用: 人 IHC, WB, ELISA, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) antibodyTP53BP1 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 350-400) antibodyTP53BP1 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (N-Term) antibodyKO Validated TP53BP1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (AA 1955-1972), (C-Term) antibodyTP53BP1 适用: 人, 小鼠, 大鼠 IHC, WB, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (pSer25), (pSer29) antibodyTP53BP1 适用: 人, 小鼠, 大鼠 ELISA, ICC, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Protein P53 Binding Protein 1 (TP53BP1) (N-Term) antibodyTP53BP1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
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别名
- TP53BP1
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背景
- P53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.Synonyms: 53BP1, Tumor suppressor p53-binding protein 1, p53-binding protein 1, p53BP1
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分子量
- approx. 213 kDa
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基因ID
- 7158
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NCBI登录号
- NP_001135451
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UniProt
- Q12888
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途径
- DNA Damage Repair
抗原
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