MAP2K4 抗体
Our Local Distributor
北京 101111
Quick Overview for MAP2K4 抗体 (ABIN498168)
抗原
See all MAP2K4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- This antibody detects endogenous levels of MEK-4 protein. (region surrounding Gln253)
-
交叉反应 （详细）
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Affinity chromatography using epitope-specific immunogen
-
纯度
- > 95 % (by SDS-PAGE)
-
-
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibody
MAP2K4 适用: 人 WB, IHC, IF, IHC (p), IP, FACS 宿主: 小鼠 Monoclonal 4B4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibodyMAP2K4 适用: 人 WB, IHC, IF, IHC (p), IP 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibodyMAP2K4 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 137-394) antibodyMAP2K4 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) antibodyMAP2K4 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5H4 unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 1-399) antibodyMAP2K4 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (AA 259-398) antibodyMAP2K4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pSer80) antibodyMAP2K4 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pSer257), (pThr261) antibodyMAP2K4 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4) (pThr261) antibodyMAP2K4 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- MAP2K4 (Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))
-
别名
- MAP2K4
-
背景
- The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38β. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.Synonyms: Dual specificity mitogen-activated protein kinase kinase 4, JNK-activating kinase 1, MAP Kinase Kinase 4, MAPKK4, MEK-4, MKK4, PRKMK4, SAPK/ERK kinase 1, SERK1, c-Jun N-terminal kinase kinase 1
-
分子量
- approx. 44 kDa
-
基因ID
- 6416
-
NCBI登录号
- NP_003001
-
UniProt
- P45985
-
途径
- MAPK Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, BCR Signaling
抗原
-
