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KIF11 抗体

KIF11 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN498151
发货至: 中国
  • 抗原 See all KIF11 抗体
    KIF11 (Kinesin Family Member 11 (KIF11))
    适用
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    宿主
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    克隆类型
    • 55
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    多克隆
    标记
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    This KIF11 antibody is un-conjugated
    应用范围
    • 65
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This antibody detects endogenous levels of Eg5 protein.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography using epitope-specific immunogen
    纯度
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product KIF11 Primary Antibody
  • 应用备注
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    KIF11 (Kinesin Family Member 11 (KIF11))
    别名
    KIF11 (KIF11 产品)
    别名
    EG5 antibody, HKSP antibody, KNSL1 antibody, MCLMR antibody, TRIP5 antibody, Eg5 antibody, Kif8 antibody, Kifl1 antibody, Knsl1 antibody, F2H17.19 antibody, F2H17_19 antibody, DDBDRAFT_0189194 antibody, DDBDRAFT_0201556 antibody, DDB_0189194 antibody, DDB_0201556 antibody, XLEg5K1 antibody, XlEg5 antibody, cos2 antibody, costal2 antibody, eg5 antibody, hksp antibody, kif11 antibody, kif11-a antibody, kif11-b antibody, kif11b antibody, knsl1 antibody, trip5 antibody, Cos2 antibody, Costal2 antibody, XLEg5K2 antibody, kif11a antibody, kinesin family member 11 antibody, P-loop containing nucleoside triphosphate hydrolases superfamily protein antibody, kinesin family member 11 S homeolog antibody, kinesin family member 11 L homeolog antibody, KIF11 antibody, Kif11 antibody, AT2G36200 antibody, kif11 antibody, kif11.S antibody, kif11.L antibody
    背景
    Eukaryotes contain a superfamily of microtubule-based motor proteins comprising Kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. Eg5 (also known as Kinesin-like protein KIF11 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of Eg5 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. Eg5 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). Eg5 is also known to be a member of the thyroid receptor interacting protein (TRIP) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone.Synonyms: EG5, KIF11, KNSL1, Kinesin-like protein 1, Kinesin-like protein KIF11, Kinesin-like spindle protein HKSP, Kinesin-related motor protein Eg5, TRIP-5, TRIP5, Thyroid receptor-interacting protein 5
    分子量
    approx. 119 kDa
    基因ID
    3832
    NCBI登录号
    NP_004514
    UniProt
    P52732
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