电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

MYB 抗体 (Internal Region)

MYB 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN498072
发货至: 中国
  • 抗原 See all MYB 抗体
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    抗原表位
    • 15
    • 11
    • 11
    • 10
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 557-569, Internal Region
    适用
    • 117
    • 52
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, Pig
    宿主
    • 97
    • 21
    • 3
    • 3
    山羊
    克隆类型
    • 103
    • 21
    多克隆
    标记
    • 80
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MYB antibody is un-conjugated
    应用范围
    • 94
    • 58
    • 44
    • 24
    • 23
    • 13
    • 13
    • 12
    • 9
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-HRDQTVKTQK ENT
    特异性
    This antibody is expected to recognize all reported isofoms (NP_001123645.1, NP_005366.2, NP_001123644.1, NP_001155128.1, NP_001155129.1, NP_001155130.1, NP_001155131.1, NP_001155132.1).
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Pig.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    免疫原
    Peptide corresponding to internal region of Human c-Myb Genename: MYB
    Top Product
    Discover our top product MYB Primary Antibody
  • 应用备注
    Peptide ELISA: Detection Limit: 1/8000. Western blot: 0.5-1.5 μg/mL. Detects a band of Approx 85 kDa in lysates of cell line Jurkat.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
    别名
    MYB (MYB 产品)
    别名
    Cmyb antibody, c-myb antibody, c-myb_CDS antibody, efg antibody, AI550390 antibody, M16449 antibody, cmyb antibody, xmyb antibody, MYB proto-oncogene, transcription factor antibody, myeloblastosis oncogene antibody, MYB proto-oncogene, transcription factor S homeolog antibody, v-myb avian myeloblastosis viral oncogene homolog antibody, MYB antibody, Myb antibody, myb.S antibody, myb antibody
    背景
    Myb is a transcriptional activator, DNA-binding protein that recognizes the sequence 5'-YAAC[GT]G-3'. It participates in the control of proliferation and differentiation of hematopoietic progenitor cells. Myb is a transcription factor related to Myc, and is expressed predominantly in haematopoietic cells and immature gastroepithelial cells. TRAF7 stimulates the sumoylation of Myb at Lys-523 and Lys-499, which are the same sites as those used for PIASy-induced sumoylation. A correlation has been established between reduction in sumoylation of Myb and increase in transcriptional activation. Negative influence on transactivation properties by the negative regulatory domain region of c-Myb depends on upon sumoylation.Synonyms: Proto-oncogene c-Myb, Transcriptional activator Myb, c-Myb
    基因ID
    4602
    NCBI登录号
    NP_005366
    UniProt
    P10242
    途径
    Chromatin Binding, Positive Regulation of Immune Effector Process
You are here:
客服