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GNAS 抗体 (Internal Region)

GNAS 适用: 人, 小鼠, 大鼠, Cow WB, EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN498036
发货至: 中国
  • 抗原 See all GNAS 抗体
    GNAS (GNAS Complex Locus (GNAS))
    抗原表位
    • 16
    • 10
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 82
    • 27
    • 23
    • 8
    • 7
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, Cow
    宿主
    • 77
    • 9
    • 1
    山羊
    克隆类型
    • 79
    • 8
    多克隆
    标记
    • 47
    • 9
    • 8
    • 7
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GNAS antibody is un-conjugated
    应用范围
    • 71
    • 42
    • 32
    • 18
    • 17
    • 9
    • 8
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    序列
    C-QAARSNSDGE KATK
    特异性
    This antibody is expected to recognize all three reported isoforms NP_000507.1, NP_001070956.1 and NP_536350.2.
    交叉反应 (详细)
    Species reactivity (expected):Bovine.
    Species reactivity (tested):Human, Mouse, Rat.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence from the internal region of the protein sequence according to NP_000507.1, NP_001070956.1, NP_001070957.1. Genename: GNAS
    Top Product
    Discover our top product GNAS Primary Antibody
  • 应用备注
    Peptide ELISA: Limit Dilution: 1/16000. Western blot: 1-3 μg/mL. Approx 45 kDa band observed in lysates of cell line Jurkat(calculated MW of 45.5 kDa according to NP_000507.1).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GNAS (GNAS Complex Locus (GNAS))
    别名
    GNAS / GSP (GNAS 产品)
    别名
    AHO antibody, C20orf45 antibody, GNAS1 antibody, GPSA antibody, GSA antibody, GSP antibody, NESP antibody, PHP1A antibody, PHP1B antibody, PHP1C antibody, POH antibody, GNAS antibody, PORGSA1 antibody, G-alpha-S antibody, 5530400H20Rik antibody, A930027G11Rik antibody, C130027O20Rik antibody, Galphas antibody, Gnas1 antibody, Gnasxl antibody, Gsa antibody, Nesp antibody, Nespl antibody, Oed-Sml antibody, Oedsml antibody, P1 antibody, P2 antibody, P3 antibody, G-alpha-s antibody, gnas-a antibody, Gnpas antibody, Nesp55 antibody, gnal antibody, Gnas antibody, GNAS complex locus antibody, guanine nucleotide-binding protein G(s) subunit alpha antibody, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus antibody, GNAS complex locus S homeolog antibody, neuroendocrine secretory protein 55-like antibody, GNAS antibody, LOC694289 antibody, LOC469986 antibody, Gnas antibody, gnas.S antibody, gnas antibody, LOC100346323 antibody, LOC100442753 antibody, LOC100732436 antibody
    背景
    GTP-binding proteins (G-proteins)are a family of heterotrimeric proteins that play a critical role in signal transduction by coupling cell surface, 7-transmembrane domain receptors to intracellular signaling pathways including second messenger generation (such as cyclic AMP, calcium and diacylglycerol), protein phosphorylation, ion channel activation, gene induction, cell growth and differentiation. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit.Synonyms: Adenylate cyclase-stimulating G alpha protein, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
    基因ID
    2778
    NCBI登录号
    NP_000507
    UniProt
    P63092
    途径
    Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Embryonic Body Morphogenesis
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