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- 抗原 See all YAP1 抗体
- YAP1 (Yes-Associated Protein 1 (YAP1))
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抗原表位
- AA 420-446
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This YAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- 纯化方法
- Purified
- 免疫原
- A portion of amino acids 420-446 from human YAP1 was used as the immunogen for this YAP antibody.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product YAP1 Primary Antibody
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anti-Yes-Associated Protein 1 (YAP1) (AA 53-161) antibody
YAP1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-Yes-Associated Protein 1 (YAP1) antibodyYAP1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Yes-Associated Protein 1 (YAP1) antibodyYAP1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A12 unconjugated
anti-Yes-Associated Protein 1 (YAP1) antibodyKO Validated YAP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Yes-Associated Protein 1 (YAP1) antibodyYAP1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Yes-Associated Protein 1 (YAP1) (AA 131-330) antibodyYAP1 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Yes-Associated Protein 1 (YAP1) (C-Term) antibodyYAP1 适用: 人, 小鼠, 大鼠, 斑马鱼, 犬, 绵羊, 马, Pig, Cow, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Yes-Associated Protein 1 (YAP1) (AA 53-162) antibodyYAP1 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F12 unconjugated
anti-Yes-Associated Protein 1 (YAP1) antibodyYAP1 适用: 人 WB, IHC (p), FACS, EIA 宿主: 小鼠 Monoclonal 1A12 unconjugated
anti-Yes-Associated Protein 1 (YAP1) antibodyYAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Titration of the YAP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the YAP antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- YAP1 (Yes-Associated Protein 1 (YAP1))
- 别名
- YAP (YAP1 产品)
- 别名
- YAP antibody, YAP2 antibody, YAP65 antibody, YKI antibody, xyap antibody, yap antibody, yap2 antibody, yap65 antibody, yki antibody, AI325207 antibody, Yap antibody, Yap65 antibody, Yki antibody, Yorkie antibody, cb194 antibody, sb:cb194 antibody, si:ch211-181p1.5 antibody, si:dkey-3b8.3 antibody, wu:fc18c04 antibody, zgc:158380 antibody, Yes associated protein 1 antibody, Yes associated protein 1 S homeolog antibody, yes-associated protein 1 antibody, Yes-associated protein 1 antibody, YAP1 antibody, yap1.S antibody, Yap1 antibody, yap1 antibody
- 背景
- YAP is a transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Plays a key role to control cell proliferation in response to cell contact. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. [UniProt]
- UniProt
- P46937
- 途径
- MAPK Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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