XRCC5 抗体 (AA 424-450)
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北京 101111
Quick Overview for XRCC5 抗体 (AA 424-450) (ABIN3029653)
抗原
See all XRCC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 424-450
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 424-450 from the human protein was used as the immunogen for this XRCC5 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the XRCC5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the XRCC5 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
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别名
- XRCC5
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背景
- The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
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UniProt
- P13010
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途径
- DNA Damage Repair
抗原
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