XRCC5 抗体 (C-Term)
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- 抗原 See all XRCC5 抗体
- XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 犬, 马, 兔, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This XRCC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- GITLITKEEA SGSSVTAEEA KKFLAPKDKP SGDTAAVFEE GGDVDDLLDM
- 预测反应
- Cow: 92%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 93%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against XRCC5. It was validated on Western Blot and immunohistochemistry.
- 纯化方法
- Protein A purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human XRCC5
- Top Product
- Discover our top product XRCC5 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 732 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
- 别名
- XRCC5 (XRCC5 产品)
- 别名
- AI314015 antibody, Ku80 antibody, Ku86 antibody, Kup80 antibody, KARP-1 antibody, KARP1 antibody, KU80 antibody, KUB2 antibody, NFIV antibody, xrcc5-a antibody, XRCC5 antibody, X-ray repair cross complementing 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog antibody, XRCC5 antibody, Xrcc5 antibody, xrcc5.L antibody
- 背景
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XRCC5 encodes the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Alias Symbols: KU80, KUB2, Ku86, NFIV, KARP1, KARP-1
Protein Interaction Partner: HUWE1, UBC, EHF, ELF3, SUMO2, SUMO3, BRCA1, ATRX, Fbxl16, NEDD8, SUMO1, MDM2, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, BMI1, EIF4B, C1QBP, RPL24, PLCB3, PRMT3, EIF3J, CUL2, CSDE1, SF1, TRMT1, SAMHD1, DNMBP, GANAB, HYOU1, NCL, NARS, MSH2, JUP, HSPA4, PARP1, TAR
Protein Size: 732 - 分子量
- 83 kDa
- 基因ID
- 7520
- NCBI登录号
- NM_021141, NP_066964
- UniProt
- Q4VBQ5
- 途径
- DNA Damage Repair
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