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Tuberin 抗体 (AA 1776-1805)

This anti-Tuberin antibody is a 兔 多克隆 antibody detecting Tuberin in ELISA, WB, IHC 和 IF. Suitable for 人.
产品编号 ABIN3029331
发货至: 中国

Quick Overview for Tuberin 抗体 (AA 1776-1805) (ABIN3029331)

抗原

See all Tuberin (TSC2) 抗体
Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

适用

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宿主

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克隆类型

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多克隆

标记

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This Tuberin antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

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    AA 1776-1805

    纯化方法

    Antigen affinity purified

    免疫原

    A portion of amino acids 1776-1805 from the human protein was used as the immunogen for this Tuberin antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Tuberin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:10-1:50,Western blot: 1:1000,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Tuberin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

    别名

    Tuberin

    背景

    Mutations in TSC2 lead to tuberous sclerosis complex. This protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking.

    UniProt

    P49815

    途径

    RTK signaling, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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