TRAF2 抗体 (AA 343-372)
Quick Overview for TRAF2 抗体 (AA 343-372) (ABIN3029149)
抗原
See all TRAF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 343-372
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纯化方法
- Purified
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免疫原
- A portion of amino acids 343-372 from the human protein was used as the immunogen for this TRAF2 antibody.
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亚型
- Ig Fraction
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anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-300) antibody
TRAF2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 238-491) antibodyTRAF2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyVerified TRAF2 适用: 人, 小鼠 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 39-188) antibodyTRAF2 适用: 人 ELISA, IHC, ICC, FACS 宿主: 小鼠 Monoclonal 5C2C3 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) antibodyTRAF2 适用: 人 WB, ELISA, IHC, IP, FACS 宿主: 兔 Monoclonal 9A5 unconjugated Recombinant Antibody
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 39-188) antibodyTRAF2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 4A12D9 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 401-501) antibodyTRAF2 适用: 人 WB, ELISA, FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 147-281) antibodyTRAF2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (AA 1-501) antibodyTRAF2 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 4C11 unconjugated
anti-TNF Receptor-Associated Factor 2 (TRAF2) (C-Term) antibodyTRAF2 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the TRAF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the TRAF2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- TRAF2 (TNF Receptor-Associated Factor 2 (TRAF2))
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别名
- TRAF2
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背景
- TRAF2 regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation, this does not depend on the TRAF2 RING-type zinc finger domain. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR. In complex with BIRC2 or BIRC3, promotes ubiquitination of IKBKE. [UniProt]
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UniProt
- Q12933
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途径
- NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Unfolded Protein Response, S100 Proteins
抗原
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