MAP3K7 抗体 (AA 574-606)
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Quick Overview for MAP3K7 抗体 (AA 574-606) (ABIN3032060)
抗原
See all MAP3K7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 574-606
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原理
- TAK1 Antibody / MAP3K7
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预测反应
- Bovine,Mouse,Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 574-606 from the human protein was used as the immunogen for this TAK1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the TAK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles
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储存条件
- -20 °C
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储存方法
- Aliquot the TAK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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别名
- TAK1
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背景
- TAK1 is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses.
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UniProt
- O43318
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途径
- NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
抗原
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