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MAP3K7 抗体 (AA 560-600)

Name: MAP3K7 抗体 (AA 560-600)
SKU: ABIN701185
Availability: OutOfStock

This 兔多克隆 antibody specifically detects MAP3K7 in WB, IHC (p), IF (cc), IF (p) 和 IHC (fro). It exhibits reactivity toward 人. It has been mentioned in 5+ publications

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti TAK1/MAP3K7 Polyclonal Antibody, Unconjugated (ABIN701185) at 1:200 followed by conjugation to the secondary antibody and DAB staining (MAP3K7 抗体 (AA 560-600))

IHC

Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-TAK1/MAP3K7 Polyclonal Antibody, Unconjugated (ABIN701185) followed by conjugation to the secondary antibody and DAB staining (MAP3K7 抗体 (AA 560-600))

IHC

Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti TAK1/MAP3K7 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (MAP3K7 抗体 (AA 560-600))

IHC (p)

3 images

(5 references)

产品编号 ABIN701185

发货至: 中国

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中国
北京 101111

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Beijing Economic Technological Development Area

Room 801-803

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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAP3K7 抗体 (AA 560-600) (ABIN701185)

抗原

See all MAP3K7 抗体

MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

适用

人

宿主

兔

克隆类型

多克隆

标记

This MAP3K7 antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product MAP3K7 Primary Antibody

抗原表位
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AA 560-600

原理

TAK1 Polyclonal Antibody

交叉反应

人, 小鼠, 大鼠, 绵羊

预测反应

Cow,Pig,Horse,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated KLH conjugated synthetic peptide derived from human MAP3K7/TAK1

亚型

IgG
anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 300-470) antibody
MAP3K7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibody
MAP3K7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Internal Region) antibody
Verified MAP3K7 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 131-160), (N-Term) antibody
MAP3K7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB34632 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 1-579) antibody
MAP3K7 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pThr184), (pThr187) antibody
MAP3K7 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (AA 471-579) antibody
MAP3K7 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3E8H4 unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (pSer412) antibody
MAP3K7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) (Thr187) antibody
MAP3K7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) antibody
KD Validated MAP3K7 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB2395 unconjugated Recombinant Antibody

应用备注

WB(1:300-5000),

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Ji, Zhang, Zhang, Fan, Liu, Yang, Hu, Liu, Dong: "MicroRNA 143-5p regulates alpaca melanocyte migration, proliferation and melanogenesis." in: Experimental dermatology, Vol. 27, Issue 2, pp. 166-171, (2018) (PubMed).

Chu, Zhao, Feng, Zhang, Liu, Cheng, Li, Shen, Cao, Li, Min: "MicroRNA-126 participates in lipid metabolism in mammary epithelial cells." in: Molecular and cellular endocrinology, Vol. 454, pp. 77-86, (2017) (PubMed).

Wang, Zhao, Yu, Feng, Zhang, Kou, Chu, Cui, Li, Zhang, Shen, Min: "Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis." in: Toxicology and applied pharmacology, Vol. 313, pp. 149-158, (2016) (PubMed).

Zhao, Zhang, Liu, Zhang, Hao, Li, Chen, Shen, Tang, Min, Meng, Wang, Yi, Zhang: "Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways." in: Scientific reports, Vol. 6, pp. 37884, (2016) (PubMed).
抗原

MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))

别名

Tak1

背景

Synonyms: TAK1, MEKK7, TGF1a, Mitogen-activated protein kinase kinase kinase 7, Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, MAP3K7
Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Mediates signal transduction of TRAF6, various cytokines including interleukin-1 (IL-1), transforming growth factor-beta (TGFB), TGFB-related factors like BMP2 and BMP4, toll-like receptors (TLR), tumor necrosis factor receptor CD40 and B-cell receptor (BCR). Ceramides are also able to activate MAP3K7/TAK1. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade and the p38 MAPK signal transduction cascade through the phosphorylation and activation of several MAP kinase kinases like MAP2K1/MEK1, MAP2K3/MKK3, MAP2K6/MKK6 and MAP2K7/MKK7. These MAP2Ks in turn activate p38 MAPKs, c-jun N-terminal kinases (JNKs) and I-kappa-B kinase complex (IKK). Both p38 MAPK and JNK pathways control the transcription factors activator protein-1 (AP-1), while nuclear factor-kappa B is activated by IKK. MAP3K7 activates also IKBKB and MAPK8/JNK1 in response to TRAF6 signaling and mediates BMP2-induced apoptosis. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK1, but not that of NF-kappa-B. Promotes TRIM5 capsid-specific restriction activity.

基因ID

6885

UniProt

O43318

途径

NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway