RUNX2 抗体 (AA 445-474)
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北京 101111
Quick Overview for RUNX2 抗体 (AA 445-474) (ABIN3032500)
抗原
See all RUNX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 445-474
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 445-474 from the human protein was used as the immunogen for this RUNX2 antibody.
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亚型
- Ig Fraction
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anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibody
RUNX2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibodyRUNX2 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) antibodyRUNX2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (pSer451) antibodyRUNX2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (Internal Region) antibodyRUNX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Titration of the RUNX2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the RUNX2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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别名
- RUNX2
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背景
- RUNX2 is a transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation. [UniProt]
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UniProt
- Q13950
抗原
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