AI848422 antibody, mKIAA0661 antibody, BRE1B antibody, RBP95 antibody, STARING antibody, ring finger protein 40 antibody, RNF40 antibody, Rnf40 antibody
背景
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.