PIK3CA 抗体 (AA 504-533)
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Quick Overview for PIK3CA 抗体 (AA 504-533) (ABIN3028924)
抗原
See all PIK3CA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 504-533
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纯化方法
- Purified
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免疫原
- A portion of amino acids 504-533 from the human protein was used as the immunogen for this PI3KCA antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PI3KCA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PI3KCA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PIK3CA (Phosphoinositide-3-Kinase, Catalytic, alpha Polypeptide (PIK3CA))
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别名
- PI3KCA
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背景
- Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
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UniProt
- P42336
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途径
- PI3K-Akt Signaling, RTK signaling, TCR Signaling, AMPK Signaling, Interferon-gamma Pathway, TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, VEGF Signaling
抗原
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