This phospho-p62 antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS207 of human p62/SQSTM1.
KO Validated
SQSTM1
适用: 人
WB, IHC, IF, IP
宿主: 兔
Monoclonal
unconjugated
应用备注
Titration of the phospho-p62 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500
限制
仅限研究用
状态
Liquid
缓冲液
In 1X PBS pH 7.4 with 0.09 % sodium azide
储存液
Sodium azide
注意事项
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Aliquot the phospho-p62 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
抗原
SQSTM1
(Sequestosome 1 (SQSTM1))
别名
p62 SQSTM1
背景
This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.