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FAS 抗体 (pTyr291)

This anti-FAS antibody is a 兔 多克隆 antibody detecting FAS in ELISA 和 DB. Suitable for 人.
产品编号 ABIN3030905
发货至: 中国

Quick Overview for FAS 抗体 (pTyr291) (ABIN3030905)

抗原

See all FAS 抗体
FAS (TNF Receptor Superfamily, Member 6 (FAS))

适用

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宿主

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克隆类型

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多克隆

标记

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This FAS antibody is un-conjugated

应用范围

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ELISA, Dot Blot (DB)
  • 抗原表位

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    pTyr291

    纯化方法

    Antigen affinity purified

    免疫原

    This phospho-FAS antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY291 of human FAS.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the phospho-FAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the phospho-FAS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    FAS (TNF Receptor Superfamily, Member 6 (FAS))

    别名

    Fas

    背景

    Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [UniProt]

    UniProt

    P25445

    途径

    p53 Pathway, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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