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PCNA 抗体 (AA 236-261)

This anti-PCNA antibody is a 小鼠 单克隆 antibody detecting PCNA in WB, IHC 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3032323
发货至: 中国

Quick Overview for PCNA 抗体 (AA 236-261) (ABIN3032323)

抗原

See all PCNA 抗体
PCNA (Proliferating Cell Nuclear Antigen (PCNA))

适用

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人, 小鼠, 大鼠

宿主

  • 143
  • 123
  • 3
小鼠

克隆类型

  • 140
  • 128
  • 1
单克隆

标记

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This PCNA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA

克隆位点

1157CT1-1-3
  • 抗原表位

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    AA 236-261

    交叉反应 (详细)

    Expected species reactivity: Bovine, Primate, Hamster

    纯化方法

    Purified

    免疫原

    A portion of amino acids 236-261 from human Proliferating Cell Nuclear Antigen was used as the immunogen for this PCNA antibody.

    亚型

    IgG1
  • 应用备注

    Titration of the PCNA antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Western blot: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the PCNA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    PCNA (Proliferating Cell Nuclear Antigen (PCNA))

    别名

    PCNA (Proliferating Cell Nuclear Antigen)

    背景

    This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

    UniProt

    P12004

    途径

    Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
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