PARP1 抗体 (AA 123-151)
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Quick Overview for PARP1 抗体 (AA 123-151) (ABIN3028937)
抗原
See all PARP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 123-151
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交叉反应 (详细)
- Expected species reactivity: Mouse
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 123-151 from the human protein was used as the immunogen for this PARP1 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PARP1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PARP1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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别名
- PARP
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背景
- This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. It is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. [UniProt]
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UniProt
- P09874
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途径
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
抗原
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