PAK2 抗体 (AA 192-222)
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Quick Overview for PAK2 抗体 (AA 192-222) (ABIN3032117)
抗原
See all PAK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 192-222
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纯化方法
- Purified
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免疫原
- A portion of amino acids 192-222 from the human protein was used as the immunogen for this PAK2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the PAK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the PAK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- PAK2 (P21-Activated Kinase 2 (PAK2))
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别名
- PAK2
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背景
- PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.
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UniProt
- Q13177
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途径
- MAPK Pathway, RTK signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
抗原
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