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GTPase NRas 抗体 (AA 147-179)

This anti-GTPase NRas antibody is a 兔 多克隆 antibody detecting GTPase NRas in WB, ELISA, IHC 和 FACS. Suitable for 人.
产品编号 ABIN3031131
发货至: 中国
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Room 801-803
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Quick Overview for GTPase NRas 抗体 (AA 147-179) (ABIN3031131)

抗原

See all GTPase NRas (NRAS) 抗体
GTPase NRas (NRAS)

适用

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宿主

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克隆类型

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多克隆

标记

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This GTPase NRas antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 抗原表位

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    AA 147-179

    交叉反应 (详细)

    Expected species reactivity: Pig

    纯化方法

    Purified

    免疫原

    A portion of amino acids 147-179 from the human protein was used as the immunogen for this NRAS antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the NRAS antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50,Flow Cytometry: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS, pH 7.4, with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the NRAS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    GTPase NRas (NRAS)

    别名

    NRAS

    背景

    NRAS is a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. This protein, which has intrinsic GTPase activity, is activated to a GTP-bound form by a GTPase activating protein and inactivated to a GDP-bound form by a guanine nucleotide-exchange factor. Defects in the gene encoding this protein are a cause of juvenile myelomonocytic leukemia (JMML).

    UniProt

    P01111

    途径

    p53 Pathway, MAPK Pathway, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
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