NLRP3 抗体 (AA 65-91)
Our Local Distributor
北京 101111
Quick Overview for NLRP3 抗体 (AA 65-91) (ABIN3032020)
抗原
See all NLRP3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 65-91
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 65-91 from the human protein was used as the immunogen for this NLRP3 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the NLRP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the NLRP3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
-
别名
- NLRP3
-
背景
- NLRP3 is a pyrin-like protein containing a pyrin domain, a nucleotide-binding site (NBS) domain, and a leucine-rich repeat (LRR) motif. This protein interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kappaB signaling, and it plays a role in the regulation of inflammation, the immune response, and apoptosis.
-
UniProt
- Q96P20
-
途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
-