MGMT 抗体 (AA 1-30)
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Quick Overview for MGMT 抗体 (AA 1-30) (ABIN3032087)
抗原
See all MGMT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-30
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纯化方法
- Purified
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免疫原
- A portion of amino acids 1-30 from the human protein was used as the immunogen for this MGMT antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the MGMT antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the MGMT antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
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别名
- MGMT
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背景
- MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
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UniProt
- P16455
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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