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JNK 抗体 (AA 358-389)

This anti-JNK antibody is a 兔 多克隆 antibody detecting JNK in WB, ELISA, IHC 和 IF. Suitable for 人.
产品编号 ABIN3031837
发货至: 中国

Quick Overview for JNK 抗体 (AA 358-389) (ABIN3031837)

抗原

See all JNK (MAPK8) 抗体
JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

适用

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宿主

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克隆类型

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多克隆

标记

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This JNK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 358-389

    交叉反应 (详细)

    Expected species reactivity: Rat

    纯化方法

    Purified

    免疫原

    A portion of amino acids 358-389 from the human protein was used as the immunogen for this JNK antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the JNK antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the JNK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))

    别名

    JNK

    背景

    JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation.

    UniProt

    P45983

    途径

    MAPK Pathway, WNT signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteins
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