IRAK4 抗体 (AA 422-449)
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北京 101111
Quick Overview for IRAK4 抗体 (AA 422-449) (ABIN3028767)
抗原
See all IRAK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 422-449
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 422-449 from the mouse protein was used as the immunogen for this Irak4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Irak4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Irak4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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别名
- Irak4
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背景
- Irak4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. Phosphorylates IRAK1 (By similarity).
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UniProt
- Q8R4K2
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途径
- NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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