IRAK4 抗体 (AA 25-52)
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北京 101111
Quick Overview for IRAK4 抗体 (AA 25-52) (ABIN3031497)
抗原
See all IRAK4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-52
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交叉反应 (详细)
- Expected species reactivity: Mouse, Bovine
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 25-52 from the human protein was used as the immunogen for this IRAK4 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the IRAK4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IRAK4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IRAK4 (Interleukin-1 Receptor-Associated Kinase 4 (IRAK4))
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别名
- IRAK4
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背景
- This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
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UniProt
- Q9NWZ3
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途径
- NF-kappaB Signaling, TLR signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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