IGF1R 抗体 (AA 19-51)
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Quick Overview for IGF1R 抗体 (AA 19-51) (ABIN3031344)
抗原
See all IGF1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-51
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交叉反应 (详细)
- Expected species reactivity: Mouse, Rat
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纯化方法
- Purified
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免疫原
- A portion of amino acids 19-51 from the human protein was used as the immunogen for this IGF1R antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the IGF1R antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the IGF1R antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
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别名
- IGF1R
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背景
- The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
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UniProt
- P08069
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途径
- RTK signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
抗原
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