HES1 抗体 (AA 102-137)
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- 抗原 See all HES1 抗体
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
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抗原表位
- AA 102-137
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适用
- 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HES1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 交叉反应 (详细)
- Expected species reactivity: Bovine, Human, Rat, Xenopus
- 纯化方法
- Antigen affinity purified
- 免疫原
- This mouse Hes1 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 102-137 amino acids from the Central region of mouse Hes1.
- 亚型
- Ig Fraction
- Top Product
- Discover our top product HES1 Primary Antibody
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- 应用备注
- Titration of the Hes1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Aliquot the Hes1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- 抗原
- HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
- 别名
- Hes1 (HES1 产品)
- 背景
- Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity).
- UniProt
- P35428
- 途径
- DNA Damage Repair
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