GSK3 beta 抗体 (AA 4-34)
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Quick Overview for GSK3 beta 抗体 (AA 4-34) (ABIN3031095)
抗原
See all GSK3 beta (GSK3b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 4-34
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交叉反应 （详细）
- Expected species reactivity: Mouse, Rat
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 4-34 from the human protein was used as the immunogen for this GSK3B antibody.
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亚型
- Ig Fraction
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anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 4-34), (N-Term) antibody
GSK3b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03816 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b 适用: 人, 小鼠 WB, IF, IP 宿主: 小鼠 Monoclonal 2E6-D6-C12 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (N-Term) antibodyGSK3b 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 30-59) antibodyGSK3b 适用: 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33) antibodyGSK3b 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 362-395) antibodyGSK3b 适用: 大鼠 WB 宿主: 兔 Polyclonal RB56577 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) (AA 2-33), (pSer9) antibodyGSK3b 适用: 人 WB 宿主: 兔 Polyclonal RB56641 unconjugated
anti-Glycogen Synthase Kinase 3 beta (GSK3b) antibodyGSK3b 适用: 人, 小鼠, 大鼠 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal 2E6-D6-C12 unconjugated
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应用备注
- Titration of the GSK3B antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the GSK3B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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别名
- GSK3B
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背景
- GSK3B is a constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. May also mediate the development of insulin resistance by regulating activation of transcription factors. [UniProt]
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UniProt
- P49841
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途径
- WNT signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
抗原
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