GSK3 beta 抗体 (AA 30-59)
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Quick Overview for GSK3 beta 抗体 (AA 30-59) (ABIN3031094)
抗原
See all GSK3 beta (GSK3b) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 30-59
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交叉反应 (详细)
- Expected species reactivity: Human, Rat
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 30-59 from the mouse protein was used as the immunogen for this Gsk3b antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Gsk3b antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Gsk3b antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))
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别名
- Gsk3b
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背景
- Participates in the Wnt signaling pathway. Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. May phosphorylate MUC1 and decrease the interaction of MUC1 with CTNNB1/beta-catenin. Phosphorylates CTNNB1/beta-catenin. Phosphorylates SNAI1 (By similarity).
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UniProt
- Q9WV60
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途径
- WNT signaling, Hedgehog Signaling, Fc-epsilon Receptor Signaling Pathway, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagy, BCR Signaling, Warburg Effect
抗原
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