BID 抗体 (AA 39-68)
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Quick Overview for BID 抗体 (AA 39-68) (ABIN3030161)
抗原
See all BID 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 39-68
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 39-68 from the mouse protein was used as the immunogen for this Bid antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the Bid antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,IHC (Paraffin): 1:50-1:100,Flow Cytometry: 1:10-1:50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the Bid antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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别名
- Bid
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背景
- Bid is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release.
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UniProt
- P70444
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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