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Bcl-2 抗体 (AA 75-110)

This anti-Bcl-2 antibody is a 兔 多克隆 antibody detecting Bcl-2 in WB, IHC, ELISA 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3030102
发货至: 中国

Quick Overview for Bcl-2 抗体 (AA 75-110) (ABIN3030102)

抗原

See all Bcl-2 (BCL2) 抗体
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Bcl-2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
  • 抗原表位

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    AA 75-110

    交叉反应 (详细)

    Expected species reactivity: Bovine

    纯化方法

    Purified

    免疫原

    A portion of amino acids 75-110 (BH3 binding domain) from the human protein was used as the immunogen for this Bcl-2 antibody.

    亚型

    Ig Fraction
  • 应用备注

    Titration of the Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:500,IHC (Paraffin): 1:10-1:50,Immunofluorescence: 1:10-1:50

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    In 1X PBS pH 7.4 with 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Aliquot the Bcl-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • 抗原

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    别名

    Bcl-2

    背景

    BCL2 is integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma.

    UniProt

    P10415

    途径

    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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