Bcl-2 抗体 (AA 87-116)
Quick Overview for Bcl-2 抗体 (AA 87-116) (ABIN3030095)
抗原
See all Bcl-2 (BCL2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 87-116
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交叉反应 (详细)
- Expected species reactivity: Bovine, Hamster, Mouse, Rat
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纯化方法
- Antigen affinity purified
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免疫原
- A portion of amino acids 87-116 from the human protein was used as the immunogen for this BCL-2 antibody.
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亚型
- Ig Fraction
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应用备注
- Titration of the BCL-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Aliquot the BCL-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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别名
- BCL-2
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背景
- This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq].
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UniProt
- P10415
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途径
- MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
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