Bcl-2 抗体 (AA 49-76)
Quick Overview for Bcl-2 抗体 (AA 49-76) (ABIN3030096)
抗原
See all Bcl-2 (BCL2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 49-76
-
纯化方法
- Antigen affinity purified
-
免疫原
- A portion of amino acids 49-76 from the human protein was used as the immunogen for this anti-Bcl-2 antibody.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- Titration of the anti-Bcl-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- In 1X PBS pH 7.4 with 0.09 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Aliquot the anti-Bcl-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
-
-
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
-
别名
- Bcl-2
-
背景
- Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
-
UniProt
- P10415
-
途径
- MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
抗原
-