The stated application concentrations are suggested starting points. Titration of the Fas antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000
限制
仅限研究用
缓冲液
Antibody in PBS with 50 % Glycerol and 0.03 % ProClin 300
储存条件
-20 °C
储存方法
Store the Fas antibody at -20°C.
抗原
FAS
(TNF Receptor Superfamily, Member 6 (FAS))
别名
Fas / CD95
背景
Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). [UniProt]