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Peroxiredoxin 4 抗体

PRDX4 适用: 人, 小鼠, 大鼠 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4952125
发货至: 中国
  • 抗原 See all Peroxiredoxin 4 (PRDX4) 抗体
    Peroxiredoxin 4 (PRDX4)
    适用
    • 54
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    • 4
    • 4
    • 4
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    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 8
    • 1
    • 1
    克隆类型
    • 51
    • 9
    多克隆
    标记
    • 36
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    • 4
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    This Peroxiredoxin 4 antibody is un-conjugated
    应用范围
    • 46
    • 29
    • 25
    • 7
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    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
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    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids SDLTHQISKDYGVYLEDSGHTLRGLFIIDDK of human Peroxiredoxin 4 were used as the immunogen for the Peroxiredoxin 4 antibody.
    亚型
    IgG
    Top Product
    Discover our top product PRDX4 Primary Antibody
  • 应用备注
    Optimal dilution of the Peroxiredoxin 4 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ICC: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the Peroxiredoxin 4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    Peroxiredoxin 4 (PRDX4)
    别名
    Peroxiredoxin 4 / PRDX4 (PRDX4 产品)
    别名
    MGC82793 antibody, prdx4 antibody, MGC79732 antibody, PRDX4 antibody, AOE37-2 antibody, PRX-4 antibody, AOE372 antibody, Prx-iv antibody, Prx4 antibody, TRANK antibody, fb59c09 antibody, wu:fb59c09 antibody, zgc:162938 antibody, peroxiredoxin 4 antibody, peroxiredoxin 4 L homeolog antibody, PRDX4 antibody, prdx4.L antibody, prdx4 antibody, Prdx4 antibody
    背景
    PRDX4 (Peroxiredoxin 4) is also known as AOE37-2. The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. Functional analysis showed that PRDX4 protects glutamine synthetase from inactivation. Yeast 2-hybrid, immunoprecipitation, and immunoblot analyses indicated that PRDX4 and PRDX1 are capable of homodimerization and heterodimerization with each other but not with the mitochondrial PRDX3. Gel mobility shift and immunoblot analysis found that PRDX4 depletes NFKB binding activity together with a reduction in the amounts of p50, p65, and phosphorylated IKBA, as well as a reduction in the expression of HIV-1 viral proteins. Expression of PRDX4, alone or with PRDX1, increased the resistance of yeast cells to oxidant-induced toxicity. Jin et al. suggested PRDX4 modulates IKBA phosphorylation in the cytoplasm and thus affects a peroxiredoxin-dependent redox step.
    UniProt
    Q13162
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