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PCSK6 抗体

PCSK6 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4952032
发货至: 中国
  • 抗原 See all PCSK6 抗体
    PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
    适用
    • 32
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 28
    • 3
    • 1
    克隆类型
    • 30
    • 2
    多克隆
    标记
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    This PCSK6 antibody is un-conjugated
    应用范围
    • 24
    • 24
    • 2
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids RNPEKQGKLKEWSLILYGTAEHPYHTFSAHQSRSRMLE of human PCSK6/PACE4 were used as the immunogen for the PACE4 antibody.
    亚型
    IgG
    Top Product
    Discover our top product PCSK6 Primary Antibody
  • 应用备注
    Optimal dilution of the PACE4 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the PACE4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    PCSK6 (Proprotein Convertase Subtilisin/kexin Type 6 (PCSK6))
    别名
    PCSK6 / PACE4 (PCSK6 产品)
    别名
    PACE4 antibody, PCSK6 antibody, SPC4 antibody, C86343 antibody, Pace4 antibody, Spc4 antibody, PACE4AIIa antibody, Xpace4 antibody, spc4 antibody, proprotein convertase subtilisin/kexin type 6 antibody, peptidase S8 antibody, proprotein convertase subtilisin/kexin type 6 L homeolog antibody, PCSK6 antibody, EAMY_RS27925 antibody, pcsk6 antibody, Pcsk6 antibody, pcsk6.L antibody
    背景
    Proprotein convertase subtilisin/kexin type 6 is an enzyme that in humans is encoded by the PCSK6 gene. This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified.
    UniProt
    P29122
    途径
    Neurotrophin Signaling Pathway, SARS-CoV-2 Protein Interactome
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