-
- 抗原 See all MAG 抗体
- MAG (Myelin Associated Glycoprotein (MAG))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MAG antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Antigen affinity
- 免疫原
- Amino acids EPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK of human MAG/SIGLEC4A were used as the immunogen for the Myelin-associated glycoprotein antibody.
- 亚型
- IgG
- Top Product
- Discover our top product MAG Primary Antibody
-
anti-Myelin Associated Glycoprotein (MAG) (AA 133-237) antibody
MAG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 25-516) antibodyMAG 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 119-208) antibodyMAG 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 439-466) antibodyMAG 适用: 人, 大鼠, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB21439 unconjugated
anti-Myelin Associated Glycoprotein (MAG) antibodyMAG 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 114-132), (N-Term) antibodyMAG 适用: 人, 大鼠, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 501-582) antibodyMAG 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 551-626) antibodyMAG 适用: 人, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (C-Term) antibodyMAG 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myelin Associated Glycoprotein (MAG) (AA 119-209) antibodyMAG 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C7 unconjugated
-
- 应用备注
- Optimal dilution of the Myelin-associated glycoprotein antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the Myelin-associated glycoprotein antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- MAG (Myelin Associated Glycoprotein (MAG))
- 别名
- MAG / Myelin-associated glycoprotein (MAG 产品)
- 别名
- GMA antibody, S-MAG antibody, SIGLEC-4A antibody, SIGLEC4A antibody, siglec-4 antibody, MAG antibody, Gma antibody, siglec-4a antibody, myelin associated glycoprotein antibody, myelin-associated glycoprotein antibody, MAG antibody, mag antibody, Mag antibody
- 背景
- MAG (Myelin-associated glycoprotein), also known as SIGLEC4A, is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor, NgR. It is thought to be involved in the process of myelination. Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse, and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth. MAG-resistant embryonic neurons were rendered MAG-sensitive by expression of NgR. MAG binds specifically to an NgR-expressing cell line in a GPI-dependent and sialic acid-independent manner. Experiments blocking NgR from interacting with MAG prevented inhibition of neurite outgrowth by MAG. In cultured human embryonic kidney (HEK) cells expressing the NOGO receptor, p75(NTR) was required for MAG-induced intracellular calcium elevation.
- UniProt
- P20916
- 途径
- Neurotrophin Signaling Pathway
-
You are here:
