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MEFV 抗体

MEFV 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4951702
发货至: 中国
  • 抗原 See all MEFV 抗体
    MEFV (Mediterranean Fever (MEFV))
    适用
    • 22
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    • 2
    • 1
    克隆类型
    • 21
    • 1
    多克隆
    标记
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    This MEFV antibody is un-conjugated
    应用范围
    • 17
    • 15
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids PSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSR of human MEFV were used as the immunogen for the MEFV antibody.
    亚型
    IgG
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  • 应用备注
    Optimal dilution of the MEFV antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the MEFV antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    MEFV (Mediterranean Fever (MEFV))
    别名
    MEFV / Mediterranean fever (MEFV 产品)
    别名
    pyrin antibody, MEFV antibody, FMF antibody, MEF antibody, TRIM20 antibody, rfp domain antibody, MEFV, pyrin innate immunity regulator antibody, Mediterranean fever antibody, MEFV antibody, Mefv antibody
    背景
    MEFV (Mediterranean fever) is a human gene that provides instructions for making a protein called pyrin (also known as marenostrin). Pyrin is produced in certain white blood cells (neutrophils, eosinophils and monocytes) that play a role in inflammation and in fighting infection. Inside these white blood cells, pyrin is found with thecytoskeleton, the structural framework that helps to define the shape, size, and movement of a cell. Pyrin's protein structure also allows it to interact with other molecules involved in fighting infection and in the inflammatory response. Although pyrin's function is not fully understood, it likely assists in keeping the inflammation process under control. Research indicates that pyrin helps regulate inflammation by interacting with the cytoskeleton. And Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed.
    UniProt
    O15553
    途径
    Positive Regulation of Endopeptidase Activity
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