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KCNA3 抗体

KCNA3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4951520
发货至: 中国
  • 抗原 See all KCNA3 抗体
    KCNA3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3))
    适用
    • 76
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    人, 小鼠, 大鼠
    宿主
    • 74
    • 3
    • 1
    克隆类型
    • 75
    • 3
    多克隆
    标记
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    This KCNA3 antibody is un-conjugated
    应用范围
    • 51
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    Western Blotting (WB)
    纯化方法
    Antigen affinity
    免疫原
    Amino acids EELRKARSNSTLSKSEYMVIEEGGMNHSAFPQ of human KCNA3 were used as the immunogen for the KCNA3 antibody.
    亚型
    IgG
    Top Product
    Discover our top product KCNA3 Primary Antibody
  • 应用备注
    Optimal dilution of the KCNA3 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the KCNA3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    KCNA3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3))
    别名
    KCNA3 / Kv1.3 (KCNA3 产品)
    别名
    Kv1.3-glyb antibody, kv1.3 antibody, Kv1.3B antibody, kcna3b-a antibody, HGK5 antibody, HLK3 antibody, HPCN3 antibody, HUKIII antibody, KV1.3 antibody, MK3 antibody, PCN3 antibody, Kca1-3 antibody, Kv1.3 antibody, Mk-3 antibody, cKv1.1 antibody, potassium voltage-gated channel subfamily A member 3 antibody, potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog antibody, potassium voltage-gated channel, shaker-related subfamily, member 3 antibody, KCNA3 antibody, kcna3.S antibody, Kcna3 antibody
    背景
    Potassium voltage-gated channel, shaker-related subfamily, member 3, also known as KCNA3 or Kv1.3, is a protein that in humans is encoded by the KCNA3 gene. This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1. And Kv1.3 has been reported to be expressed in the inner mitochondrial membrane in lymphocytes. The apoptotic protein Bax has been suggested to insert into theouter mitochondrial membrane and occlude the pore of Kv1.3 via a lysine residue. Thus, Kv1.3 modulation may be one of many mechanisms that contribute to apoptosis.
    UniProt
    P22001
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