CSNK1A1 抗体
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北京 101111
Quick Overview for CSNK1A1 抗体 (ABIN4950677)
抗原
See all CSNK1A1 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity
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免疫原
- Amino acids DIYLAINITNGEEVAVKLESQKARHPQLLYESKLYKILQ of human CSNK1A1 were used as the immunogen for the CSNK1A1 antibody.
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亚型
- IgG
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anti-Casein Kinase 1, alpha 1 (CSNK1A1) (Internal Region) antibody
CSNK1A1 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyKD Validated CSNK1A1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB125 unconjugated Recombinant Antibody
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 100-200) antibodyCSNK1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 30-68), (N-Term) antibodyCSNK1A1 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (pTyr294) antibodyCSNK1A1 适用: 人, 大鼠 WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 2-337), (Isoform alpha) antibodyCSNK1A1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyCSNK1A1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyCSNK1A1 适用: 人, 大鼠, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) antibodyCSNK1A1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 3C10F7 unconjugated
anti-Casein Kinase 1, alpha 1 (CSNK1A1) (AA 130-337) antibodyCSNK1A1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal dilution of the CSNK1A1 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CSNK1A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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别名
- CSNK1A1
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背景
- Casein kinase I isoform alpha is an enzyme that in humans is encoded by the CSNK1A1 gene. The CSNK1A1 gene is mapped to chromosome 5q32 based on an alignment of the CSNK1A1 sequence with the genomic sequence (GRCh37). It is reported that both screens identified CK1-alpha as a bifunctional regulator of NF-kappa-B. CK1-alpha dynamically associates with the CBM complex on T cell receptor engagement to participate in cytokine production and lymphocyte proliferation. However, CK1-alpha kinase activity has a contrasting role by subsequently promoting the phosphorylation and inactivation of CARMA1. CK1-alpha has thus a dual 'gating' function which first promotes and then terminates receptor-induced NF-kappa-B. ABC DLBCL cells required CK1-alpha for constitutive NF-kappa-B activity, indicating that CK1-alpha functions as a conditionally essential malignancy gene.
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UniProt
- P48729
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途径
- WNT signaling, Hedgehog Signaling
抗原
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