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CD58 抗体

CD58 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4950496
发货至: 中国
  • 抗原 See all CD58 抗体
    CD58
    适用
    • 73
    • 5
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    宿主
    • 37
    • 36
    克隆类型
    • 37
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    多克隆
    标记
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    This CD58 antibody is un-conjugated
    应用范围
    • 40
    • 33
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    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity
    免疫原
    Amino acids F29-R215 from the human protein were used as the immunogen for the CD58 antibody.
    亚型
    IgG
    Top Product
    Discover our top product CD58 Primary Antibody
  • 应用备注
    Optimal dilution of the CD58 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (FFPE): 0.5-1 μg/mL, FACS: 1-3 μg/10^6 cells
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the CD58 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    CD58
    别名
    CD58 / LFA3 (CD58 产品)
    别名
    LFA-3 antibody, LFA3 antibody, ag3 antibody, CD58 molecule antibody, CD58 antibody
    背景
    CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to. The LFA3 gene is mapped to chromosome 1p13, which is the same location as CD2.
    UniProt
    P19256
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