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CD14 抗体 (AA 65-327)

This anti-CD14 antibody is a 兔 多克隆 antibody detecting CD14 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4950462
发货至: 中国

Quick Overview for CD14 抗体 (AA 65-327) (ABIN4950462)

抗原

See all CD14 抗体
CD14

适用

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人, 小鼠, 大鼠

宿主

  • 226
  • 67
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克隆类型

  • 250
  • 65
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多克隆

标记

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This CD14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 37
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    AA 65-327

    纯化方法

    Antigen affinity

    免疫原

    Amino acids 65-327 of human CD14 were used as the immunogen for the CD14 antibody.

    亚型

    IgG
  • 应用备注

    Optimal dilution of the CD14 antibody should be determined by the researcher.\. Western blot: 0.1-0.5 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the CD14 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    CD14

    别名

    CD14

    背景

    CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. This gene is located at bands 5q23-q31. The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.

    UniProt

    P08571

    途径

    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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