TSHR, A Chain 抗体
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- 抗原 See all TSHR, A Chain products
- TSHR, A Chain (Thyroid Stimulating Hormone Receptor, A Chain (TSHR, A Chain))
- 适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TSHR, A Chain antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Protein G affinity chromatography
- 免疫原
- Recombinant human TSH Receptor alpha chain protein was used as the immunogen for this TSHR antibody.
- 克隆位点
- TSHRA-1402
- 亚型
- IgG
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anti-Thyroid Stimulating Hormone Receptor, A Chain (TSHR, A Chain) antibody
TSHR, A Chain 适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal TSHRA-1402 unconjugated
anti-Thyroid Stimulating Hormone Receptor, A Chain (TSHR, A Chain) antibodyTSHR, A Chain 适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal SPM223 unconjugated
anti-Thyroid Stimulating Hormone Receptor, A Chain (TSHR, A Chain) antibodyTSHR, A Chain 适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal SPM223 unconjugated
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- 应用备注
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the TSHR antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/10^6 cells in 0.1ml,IF: 1-2 μg/mL,IHC (FFPE): 0.5-1 μg/mL
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
- 储存液
- Azide free
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store the TSHR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- 抗原
- TSHR, A Chain (Thyroid Stimulating Hormone Receptor, A Chain (TSHR, A Chain))
- 别名
- Thyroid Stimulating Hormone Receptor / TSHR (alpha chain) (TSHR, A Chain 产品)
- 背景
- Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Graves disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
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