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Desmoglein 1 抗体 (Internal Region)

DSG1 适用: 人 WB, IF, FACS, IP 宿主: 小鼠 Monoclonal 27B2 unconjugated
产品编号 ABIN4949604
发货至: 中国
  • 抗原 See all Desmoglein 1 (DSG1) 抗体
    Desmoglein 1 (DSG1)
    抗原表位
    • 8
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 86
    • 23
    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 56
    • 30
    • 1
    小鼠
    克隆类型
    • 51
    • 36
    单克隆
    标记
    • 38
    • 9
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This Desmoglein 1 antibody is un-conjugated
    应用范围
    • 48
    • 27
    • 27
    • 21
    • 20
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)
    纯化方法
    Protein G affinity chromatography
    免疫原
    A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the DSG1 antibody.
    克隆位点
    27B2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product DSG1 Primary Antibody
  • 应用备注
    Optimal dilution of the DSG1 antibody should be determined by the researcher.\. FACS: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 1-2 μg/mL,WB: 0.5-1 μg/mL,Immunoprecipitation: suitable
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store the DSG1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
  • 抗原
    Desmoglein 1 (DSG1)
    别名
    Desmoglein 1 / DSG1 (DSG1 产品)
    别名
    CDHF4 antibody, DG1 antibody, DSG antibody, PPKS1 antibody, SPPK1 antibody, DSG-1 antibody, DSG1 antibody, Dsg1b antibody, Dsg1c antibody, desmoglein 1 antibody, desmoglein 4 antibody, DSG1 antibody, DSG4 antibody, Dsg1 antibody
    背景
    Desmoglein 1 (DSG1) is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
    途径
    Cell-Cell Junction Organization
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