TRPC5 抗体 (Trp5)
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- 抗原 See all TRPC5 抗体
- TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))
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抗原表位
- AA 827-845, Trp5
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TRPC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Detects ~110 kDa protein.
- 产品特性
- Synonyms: TRP-5, Short transient receptor potential channel 5
- 纯化方法
- Protein G Chromatography.
- 免疫原
- Synthetic peptide amino acids 827-845 of Human TrpC5.
- 克隆位点
- S67-15
- 亚型
- IgG2b
- Top Product
- Discover our top product TRPC5 Primary Antibody
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anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (FITC)
TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) FITC
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibodyTRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) unconjugated
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (HRP)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) HRP
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (Biotin)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) Biotin
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (PE)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) PE
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (APC)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) APC
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (PerCP)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) PerCP
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (Atto 488)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) Atto 488
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (Atto 594)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) Atto 594
anti-Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) (AA 827-845) antibody (Atto 390)TRPC5 适用: 人 WB, IHC, IP, AA 宿主: 小鼠 Monoclonal N67-15 (Formerly S67-15) Atto 390
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- 应用备注
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Western blot: 1 μg/mL (if results are poor, use lysate without boiling, heat at 37 °C for 15 minutes).1 μg/mL was sufficient for detection of Kv3.4 in 10 μg of Rat brain lysate by colorimetricimmunoblot analysis using Goat anti-mouse IgG: HRP as the secondary antibody. Immunoprecipitation: 1.0-10 μg/mLImmunofluorescence: 1.0-10 μg/mLImmunocytochemistry: 0.1-1.0 μg/mLImmunohistochemistry: 0.1-1.0 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4 containing 50 % Glycerol as stabilizer and 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- TRPC5 (Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5))
- 别名
- TRPC5 (TRPC5 产品)
- 别名
- trpc5 antibody, wu:fi73f08 antibody, TRPC5 antibody, Trpc5 antibody, TRP5 antibody, CCE2 antibody, TRP-5 antibody, Trrp5 antibody, trp antibody, transient receptor potential cation channel, subfamily C, member 5a antibody, transient receptor potential cation channel subfamily C member 5 antibody, transient receptor potential cation channel, subfamily C, member 5 antibody, trpc5a antibody, TRPC5 antibody, Trpc5 antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). Transient receptor potential cation channel, subfamily C, member 5, also known as TRPC5, is a subtype of the TRPC family of mammalian transient receptor potential ion channels. Homomultimeric TRPC5 and heteromultimeric TRPC5-TRPC1 channels are activated by extracellular reduced thioredoxin (3). This activation probably plays a role in rheumatoid arthritis. It has also been recently found to be involved in the action on anaesthetics such as choloform, halothane and propofol (4).Synonyms: Short transient receptor potential channel 5, TRP-5, Transient receptor protein 5
- 基因ID
- 7224
- UniProt
- Q9UL62
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