Kv3.4 抗体 (AA 175-192)
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- 抗原 See all Kv3.4 (KCNC4) 抗体
- Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))
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抗原表位
- AA 175-192
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Kv3.4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Detects ~70 kDa protein (100 kDa in brain due to glycosylation).
- 产品特性
- Synonyms: Potassium voltage-gated channel subfamily C member 4, Voltage-gated potassiumchannel subunit Kv3.4, KSHIIIC
- 纯化方法
- Protein G Chromatography.
- 免疫原
- Synthetic peptide amino acids 175-192 of Rat Kv3. 4 (accession number Q63734)AA Sequence: GDEAGDDERELALQRLGP
- 克隆位点
- S72-16
- 亚型
- IgG1
- Top Product
- Discover our top product KCNC4 Primary Antibody
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anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) antibody
KCNC4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) (Ser676) antibodyKCNC4 适用: 人, 小鼠, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) (AA 252-301) antibodyKCNC4 适用: 人, 猴, 马, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) (N-Term) antibodyKCNC4 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) (AA 490-538) antibodyKCNC4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) (Middle Region) antibodyKCNC4 适用: 人, 小鼠, 大鼠, 马, Cow, 犬, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4) (AA 177-195), (Intracellular), (N-Term) antibodyKCNC4 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot: 1 μg/mL1 μg/mL was sufficient for detection of Kv3.4 in 10 μg of Rat brain lysate by colorimetricimmunoblot analysis using Goat anti-mouse IgG: HRP as the secondary antibody. Immunoprecipitation: 1.0-10 μg/mLImmunofluorescence: 1.0-10 μg/mLImmunocytochemistry: 0.1-1.0 μg/mLImmunohistochemistry: 0.1-1.0 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS, pH 7.4 containing 50 % Glycerol as stabilizer and 0.09 % Sodium Azide as preservative.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))
- 别名
- KCNC4 (KCNC4 产品)
- 别名
- C1orf30 antibody, HKSHIIIC antibody, KSHIIIC antibody, KV3.4 antibody, AI850292 antibody, Kcr2-4 antibody, Kv3.4 antibody, potassium voltage-gated channel subfamily C member 4 antibody, potassium channel, voltage gated Shaw related subfamily C, member 4 antibody, potassium voltage gated channel, Shaw-related subfamily, member 4 antibody, KCNC4 antibody, kcnc4 antibody, Kcnc4 antibody
- 背景
- Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by chemical or electrical signals, temperature, or mechanical forces. There are a few main classifications of gated ion channels. There are voltage- gated ion channels, ligandgated, other gating systems and finally those that are classified differently, having more exotic characteristics. The first are voltage- gated ion channels which open and close in response to membrane potential. These are then separated into sodium, calcium, potassium, proton, transient receptor, and cyclic nucleotide-gated channels, each of which is responsible for a unique role. Ligand-gated ion channels are also known as ionotropic receptors, and they open in response to specific ligand molecules binding to the extracellular domain of the receptor protein. The other gated classifications include activation and inactivation by second messengers, inwardrectifier potassium channels, calcium-activated potassium channels, two-pore-domain potassium channels, light-gated channels, mechano-sensitive ion channels and cyclic nucleotide-gated channels. Finally, the other classifications are based on less normal characteristics such as two-pore channels, and transient receptor potential channels (2). Kv3.4, a member of the Shaw subfamily, may play important roles in maintaining normal function of the corneal epithelium (3). Kv3.4 is also over-expressed in the early stages of Alzheimer's disease, and therefore represents a novel therapeutic target for this disease (4).Synonyms: KSHIIIC, Potassium voltage-gated channel subfamily C member 4, Voltage-gated potassium channel subunit Kv3.4
- 基因ID
- 684516
- UniProt
- Q63734
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